A streamlined platform for analyzing tera-scale DDA and DIA mass spectrometry data enables highly sensitive immunopeptidomics

A streamlined platform for analyzing tera-scale DDA and DIA mass spectrometry data enables highly sensitive immunopeptidomics

Immunopeptidomics benefits from highly sensitive mass spectrometry (MS). Here, the authors present a computational platform for integrating data-dependent and -independent acquisition MS approaches, and demonstrate its utility for deeper immunopeptidome profiling.

Bibliographic Details
Main Authors: Lei Xin, Rui Qiao, Xin Chen, Hieu Tran, Shengying Pan, Sahar Rabinoviz, Haibo Bian, Xianliang He, Brenton Morse, Baozhen Shan, Ming Li
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-30867-7

Internet

https://doi.org/10.1038/s41467-022-30867-7

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