Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis

Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis

Intestinal ischemia reperfusion (II/R) is a clinical emergency that frequently occurs in a variety of clinical conditions. Severe intestinal injury results in the release of cytotoxic substances and inflammatory mediators which can activate local inflammatory response and bacterial translocation. Th...

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Bibliographic Details
Main Authors: Wenlian Li, Kejia Yang, Bin Li, Yunxiang Wang, Jing Liu, Dapeng Chen, Yunpeng Diao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Pharmacology
Subjects:
corilagin
ischemia-reperfusion
intestine
lung
NLRP3
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1060104/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1060104/full

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