Geometric transformation adaptive optics (GTAO) for volumetric deep brain imaging through gradient-index lenses

Abstract The advance of genetic function indicators has enabled the observation of neuronal activities at single-cell resolutions. A major challenge for the applications on mammalian brains is the limited optical access depth. Currently, the method of choice to access deep brain structures is to ins...

Full description

Bibliographic Details
Main Authors: Yuting Li, Zongyue Cheng, Chenmao Wang, Jianian Lin, Hehai Jiang, Meng Cui
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45434-5