Expression of ADP receptor P2Y12, thromboxane A2 receptor and C-type lectin-like receptor 2 in cord blood-derived megakaryopoiesis

Expression of ADP receptor P2Y12, thromboxane A2 receptor and C-type lectin-like receptor 2 in cord blood-derived megakaryopoiesis

The ADP receptor P2Y12, the thromboxane A2 receptor (TXA2R) and the C-type lectin-like receptor 2 (CLEC-2) mediate platelet activation by different mechanisms. Only little is known about the expression of the receptors in human megakaryopoiesis. Our study aimed to establish a flow cytometry (FC) met...

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Bibliographic Details
Main Authors: Catharina Gerhards, Stefanie Uhlig, Mani Etemad, Foteini Christodoulou, Karen Bieback, Harald Klüter, Peter Bugert
Format: Article
Language:English
Published: Taylor & Francis Group 2021-07-01
Series:Platelets
Subjects:
inherited platelet disorder
megakaryopoiesis
platelet function
receptor expression
Online Access:http://dx.doi.org/10.1080/09537104.2020.1782868

Internet

http://dx.doi.org/10.1080/09537104.2020.1782868

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