Real time imaging of single extracellular vesicle pH regulation in a microfluidic cross-flow filtration platform

Riazanski et al describe a platform to capture extracellular vesicles (EVs) using a nanoporous silicon nitride membrane, investigate the expression of NHE1 protein on the surface of EVs and monitor the transport of Na+ and H+ at the single EV level. The authors report a mechanistic function of the p...

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Bibliographic Details
Main Authors: Vladimir Riazanski, Gerardo Mauleon, Kilean Lucas, Samuel Walker, Adriana M. Zimnicka, James L. McGrath, Deborah J. Nelson
Format: Article
Language:English
Published: Nature Portfolio 2022-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02965-7