High co-expression of immune checkpoint receptors PD-1, CTLA-4, LAG-3, TIM-3, and TIGIT on tumor-infiltrating lymphocytes in early-stage breast cancer

High co-expression of immune checkpoint receptors PD-1, CTLA-4, LAG-3, TIM-3, and TIGIT on tumor-infiltrating lymphocytes in early-stage breast cancer

Abstract High expression of immune checkpoint receptors (ICRs) in the tumor microenvironment regulates the anti-tumor response. In this study, the differential expressions of ICRs on tumor-infiltrating lymphocytes (TILs) in patients with early-stage breast cancer were investigated. The study include...

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Bibliographic Details
Main Authors: Baran Mollavelioglu, Esin Cetin Aktas, Neslihan Cabioglu, Aykhan Abbasov, Semen Onder, Selman Emiroglu, Mustafa Tükenmez, Mahmut Muslumanoglu, Abdullah Igci, Gunnur Deniz, Vahit Ozmen
Format: Article
Language:English
Published: BMC 2022-10-01
Series:World Journal of Surgical Oncology
Subjects:
Early-stage breast cancer
TIL
NK
PD-1
CTLA-4
TIGIT
Online Access:https://doi.org/10.1186/s12957-022-02810-z

Internet

https://doi.org/10.1186/s12957-022-02810-z

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