Microemulsions as Lipid Nanosystems Loaded into Thermoresponsive In Situ Microgels for Local Ocular Delivery of Prednisolone

Microemulsions as Lipid Nanosystems Loaded into Thermoresponsive In Situ Microgels for Local Ocular Delivery of Prednisolone

This study aimed to develop and evaluate thermoresponsive in situ microgels for the local ocular delivery of prednisolone (PRD) (PRD microgels) to improve drug bioavailability and prolong ocular drug residence time. Lipid nanosystems of PRD microemulsions (PRD-MEs) were prepared and evaluated at a d...

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Bibliographic Details
Main Authors: Rania Hamed, Amani D. Abu Kwiak, Yasmeen Al-Adhami, Alaa M. Hammad, Rana Obaidat, Osama H. Abusara, Rana Abu Huwaij
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
Pluronic<sup>®</sup> F127
kolliphor<sup>®</sup> P188 (F68)
prednisolone
in situ thermoresponsive microgel
rheological properties
mucoadhesion
Online Access:https://www.mdpi.com/1999-4923/14/9/1975

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https://www.mdpi.com/1999-4923/14/9/1975

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