Hsp40 overexpression in pacemaker neurons delays circadian dysfunction in a Drosophila model of Huntington's disease

Circadian disturbances are early features of neurodegenerative diseases, including Huntington's disease (HD). Emerging evidence suggests that circadian decline feeds into neurodegenerative symptoms, exacerbating them. Therefore, we asked whether known neurotoxic modifiers can suppress circadian...

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Bibliographic Details
Main Authors: Pavitra Prakash, Arpit Kumar Pradhan, Vasu Sheeba
Format: Article
Language:English
Published: The Company of Biologists 2022-06-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/15/6/dmm049447