Inference for Stochastic Chemical Kinetics Using Moment Equations and System Size Expansion.

Quantitative mechanistic models are valuable tools for disentangling biochemical pathways and for achieving a comprehensive understanding of biological systems. However, to be quantitative the parameters of these models have to be estimated from experimental data. In the presence of significant stoc...

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Bibliographic Details
Main Authors: Fabian Fröhlich, Philipp Thomas, Atefeh Kazeroonian, Fabian J Theis, Ramon Grima, Jan Hasenauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005030