Analysis of cell-free DNA concentration, fragmentation patterns and TP53 gene expression in mammary tumor-bearing dogs: A pilot study

Analysis of cell-free DNA concentration, fragmentation patterns and TP53 gene expression in mammary tumor-bearing dogs: A pilot study

IntroductionLiquid biopsy based on the analysis of circulating cell-free DNA (cfDNA), as well as on detection of point mutations by digital droplet PCR (ddPCR), has revolutionized the research in oncology. In recent years, this technique has been pioneering in veterinary medicine since it is a minim...

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Hlavní autoři: Silvia Guil-Luna, Raquel Sánchez-Céspedes, Aurora Rivas Crespo, María Dolores Fernández, José Andrés Fernández Sarmiento, Antonio Rodríguez-Ariza, Yolanda Millán
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2023-03-01
Edice:Frontiers in Veterinary Science
Témata:
canine mammary tumors
liquid biopsy
p53 mutation detection
cell-free DNA
tumor biomarkers
On-line přístup:https://www.frontiersin.org/articles/10.3389/fvets.2023.1157878/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1157878/full

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