Genome-wide pathway association studies of multiple correlated quantitative phenotypes using principle component analyses.

Genome-wide pathway association studies provide novel insight into the biological mechanism underlying complex diseases. Current pathway association studies primarily focus on single important disease phenotype, which is sometimes insufficient to characterize the clinical manifestations of complex d...

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Bibliographic Details
Main Authors: Feng Zhang, Xiong Guo, Shixun Wu, Jing Han, Yongjun Liu, Hui Shen, Hong-Wen Deng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3532454?pdf=render