Research progress on the role of lncRNA–miRNA networks in regulating adipogenic and osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporosis

Research progress on the role of lncRNA–miRNA networks in regulating adipogenic and osteogenic differentiation of bone marrow mesenchymal stem cells in osteoporosis

Osteoporosis (OP) is characterized by a decrease in osteoblasts and an increase in adipocytes in the bone marrow compartment, alongside abnormal bone/fat differentiation, which ultimately results in imbalanced bone homeostasis. Bone marrow mesenchymal stem cells (BMSCs) can differentiate into osteob...

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Bibliographic Details
Main Authors: Fangyu An, Xiaxia Wang, Chunmei Wang, Ying Liu, Bai Sun, Jie Zhang, Peng Gao, Chunlu Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Endocrinology
Subjects:
osteoporosis
bone marrow mesenchymal stem cells
adipogenic-osteogenic differentiation
lncRNA-miRNA network
crosstalk regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1210627/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1210627/full

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