Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
The importance of the tumor microenvironment for cancer progression and therapeutic resistance is an emerging focus of cancer biology. Hypoxia, or low oxygen, is a hallmark of solid tumors that promotes metastasis and represents a significant obstacle to successful cancer therapy. In response to hyp...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-04-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3921/6/2/27 |