The Evolving Landscape of Leptomeningeal Cancer from Solid Tumors: A Systematic Review of Clinical Trials

The Evolving Landscape of Leptomeningeal Cancer from Solid Tumors: A Systematic Review of Clinical Trials

Leptomeningeal carcinomatosis (LMC) is a fatal but uncommon complication occurring in 5–15% of patients with stage IV cancer. Current treatment options are ineffective at managing leptomeningeal spread, with a median overall survival (mOS) of 2–6 months. We aimed to conduct a systematic review of th...

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Bibliographic Details
Main Authors: Lina Marenco-Hillembrand, Michael A. Bamimore, Julio Rosado-Philippi, Blake Perdikis, David N. Abarbanel, Alfredo Quinones-Hinojosa, Kaisorn L. Chaichana, Wendy J. Sherman
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
leptomeningeal cancer
carcinomatous meningitis
neoplastic meningitis
clinical trial
Online Access:https://www.mdpi.com/2072-6694/15/3/685

Internet

https://www.mdpi.com/2072-6694/15/3/685

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