Heme Oxygenase-1 Contributes to Both the Engulfment and the Anti-Inflammatory Program of Macrophages during Efferocytosis

Heme oxygenase-1 (HO-1) plays a vital role in the catabolism of heme and yields equimolar amounts of biliverdin, carbon monoxide, and free iron. We report that macrophages engulfing either the low amount of heme-containing apoptotic thymocytes or the high amount of heme-containing eryptotic red bloo...

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Bibliographic Details
Main Authors: Éva Fige, Judit Szendrei, László Sós, Izabela Kraszewska, László Potor, József Balla, Zsuzsa Szondy
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/3/652