Peptides against Low Density Lipoprotein (LDL) Aggregation Inhibit Intracellular Cholesteryl Ester Loading and Proliferation of Pancreatic Tumor Cells

Peptides against Low Density Lipoprotein (LDL) Aggregation Inhibit Intracellular Cholesteryl Ester Loading and Proliferation of Pancreatic Tumor Cells

Dyslipidemia, metabolic disorders and/or obesity are postulated as risk factors for pancreatic ductal adenocarcinoma (PDAC). The majority of patients with these metabolic alterations have low density lipoproteins (LDLs) with increased susceptibility to become aggregated in the extracellular matrix (...

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Bibliographic Details
Main Authors: Aleyda Benitez-Amaro, Neus Martínez-Bosch, Noemí Manero-Rupérez, Lene Claudi, Maria Teresa La Chica Lhoëst, Marta Soler, Lia Ros-Blanco, Pilar Navarro, Vicenta Llorente-Cortés
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
anti-LDL aggregation peptides
LDL atherogenicity
cholesteryl esters
pancreatic ductal adenocarcinoma
Online Access:https://www.mdpi.com/2072-6694/14/4/890

Internet

https://www.mdpi.com/2072-6694/14/4/890

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