2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles

2-Hydroxyoleic Acid as a Self-Assembly Inducer for Anti-Cancer Drug-Centered Nanoparticles

A potent nontoxic antitumor drug, 2-hydroxyoleic acid (<b>6</b>, 2OHOA) used for membrane lipid therapy, was selected as a self-assembly inducer due to its ability to form nanoparticles (NPs) in water. For this purpose, it was conjugated with a series of anticancer drugs through a disulf...

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Bibliographic Details
Main Authors: Antonia I. Antoniou, Giulia Nordio, Maria Luisa Di Paolo, Eleonora Colombo, Beatrice Gaffuri, Laura Polito, Arianna Amenta, Pierfausto Seneci, Lisa Dalla Via, Dario Perdicchia, Daniele Passarella
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceuticals
Subjects:
2-hydroxyoleic acid (2OHOA)
methyl 2-hydroxyoleate
nanoassemblies
conjugates
anticancer drugs
biphasic mesothelioma (MSTO-211H)
Online Access:https://www.mdpi.com/1424-8247/16/5/722

Internet

https://www.mdpi.com/1424-8247/16/5/722

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