Integrative modeling of the HIV-1 ribonucleoprotein complex.

A coarse-grain computational method integrates biophysical and structural data to generate models of HIV-1 genomic RNA, nucleocapsid and integrase condensed into a mature ribonucleoprotein complex. Several hypotheses for the initial structure of the genomic RNA and oligomeric state of integrase are...

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Bibliographic Details
Main Authors: David S Goodsell, Andrew Jewett, Arthur J Olson, Stefano Forli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007150