Transcriptome and single-cell analysis reveal the contribution of immunosuppressive microenvironment for promoting glioblastoma progression

Transcriptome and single-cell analysis reveal the contribution of immunosuppressive microenvironment for promoting glioblastoma progression

Graphical AbstractOverview of the study design. (A) We firstly identified five GBM progression related pathways. By performing functional enrichment analysis on gene sets obtained from three perspectives, such as genes co-survival in TCGA-GBM and CGGA cohort, DEGs of high and low risk groups, and DE...

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Bibliographic Details
Main Authors: Lulu Ni, Ping Sun, Sujuan Zhang, Bin Qian, Xu Chen, Mengrui Xiong, Bing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
immunosuppression
GBM
WGCNA
TAM
single-cell
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1051701/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1051701/full

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