TMEM163 Regulates ATP-Gated P2X Receptor and Behavior

TMEM163 Regulates ATP-Gated P2X Receptor and Behavior

Summary: Fast purinergic signaling is mediated by ATP and ATP-gated ionotropic P2X receptors (P2XRs), and it is implicated in pain-related behaviors. The properties exhibited by P2XRs vary between those expressed in heterologous cells and in vivo. Several modulators of ligand-gated ion channels have...

Full description

Bibliographic Details
Main Authors: Elizabeth J. Salm, Patrick J. Dunn, Lili Shan, Miwako Yamasaki, Nathalie M. Malewicz, Taisuke Miyazaki, Joongkyu Park, Akio Sumioka, R. Richard L. Hamer, Wei-Wu He, Megumi Morimoto-Tomita, Robert H. LaMotte, Susumu Tomita
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
ion channel
P2X receptor
ATP
modulator
channel
pharmacology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720306744

Internet

http://www.sciencedirect.com/science/article/pii/S2211124720306744

Similar Items