Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65

Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65

Herpes simplex virus type 2 (HSV-2) is a prevalent human pathogen and the main cause of genital herpes. After initial infection, HSV-2 can establish lifelong latency within dorsal root ganglia by evading the innate immunity of the host. NF-κB has a crucial role in regulating cell proliferation, infl...

Full description

Bibliographic Details
Main Authors: Huimin Hu, Ming Fu, Chuntian Li, Binman Zhang, Yuncheng Li, Qinxue Hu, Mudan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
HSV-2
ICP22
NF-κB
p65
immune evasion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.983502/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.983502/full

Similar Items