Structure of a Bacterial Virus DNA-Injection Protein Complex Reveals a Decameric Assembly with a Constricted Molecular Channel.

The multi-layered cell envelope structure of Gram-negative bacteria represents significant physical and chemical barriers for short-tailed phages to inject phage DNA into the host cytoplasm. Here we show that a DNA-injection protein of bacteriophage Sf6, gp12, forms a 465-kDa, decameric assembly in...

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Bibliographic Details
Main Authors: Haiyan Zhao, Jeffrey A Speir, Tsutomu Matsui, Zihan Lin, Lingfei Liang, Anna Y Lynn, Brittany Varnado, Thomas M Weiss, Liang Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4755594?pdf=render