Identification of Hotspot Mutations in the N Gene of SARS-CoV-2 in Russian Clinical Samples That May Affect the Detection by Reverse Transcription-PCR

Sensitive and reliable diagnostic test systems based on real-time PCR are of great importance in the fight against the ongoing SARS-CoV-2 pandemic. The genetic variability of the SARS-CoV-2 virus leads to the accumulation of mutations, some of which may affect the sensitivity of modern PCR assays. T...

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Bibliographic Details
Main Authors: Sergei A. Kiryanov, Tatiana A. Levina, Maria V. Konopleva, Anatoly P. Suslov
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/1/147