Lower Circulating Cytotoxic T-Cell Frequency and Higher Intragraft Granzyme-B Expression Are Associated with Inflammatory Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Recipients

Lower Circulating Cytotoxic T-Cell Frequency and Higher Intragraft Granzyme-B Expression Are Associated with Inflammatory Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Recipients

<i>Background and Objectives:</i> Inflammatory interstitial fibrosis and tubular atrophy (i-IFTA) is an inflammation in the area of tubular atrophy and fibrosis. i-IFTA is poorly associated with graft outcome and associated with infiltration of inflammatory mononuclear cells. A cytotoxic...

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Bibliographic Details
Main Authors: Brijesh Yadav, Narayan Prasad, Vinita Agrawal, Vikas Agarwal, Manoj Jain
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Medicina
Subjects:
stable graft function
inflammatory interstitial fibrosis and tubular atrophy
cytotoxic T lymphocyte
granzyme B
Online Access:https://www.mdpi.com/1648-9144/59/6/1175

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https://www.mdpi.com/1648-9144/59/6/1175

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