Type II Secretion Substrates of <italic toggle="yes">Legionella pneumophila</italic> Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane

ABSTRACT Legionella pneumophila replicates in macrophages in a host-derived phagosome, termed the Legionella-containing vacuole (LCV). While the translocation of type IV secretion (T4S) effectors into the macrophage cytosol is well established, the location of type II secretion (T2S) substrates in t...

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Bibliographic Details
Main Authors: Hilary K. Truchan, Harry D. Christman, Richard C. White, Nakisha S. Rutledge, Nicholas P. Cianciotto
Format: Article
Language:English
Published: American Society for Microbiology 2017-07-01
Series:mBio
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mBio.00870-17