GTP-Bound Escherichia coli FtsZ Filaments Are Composed of Tense Monomers: a Dynamic Nuclear Polarization-Nuclear Magnetic Resonance Study Using Interface Detection

GTP-Bound Escherichia coli FtsZ Filaments Are Composed of Tense Monomers: a Dynamic Nuclear Polarization-Nuclear Magnetic Resonance Study Using Interface Detection

ABSTRACT FtsZ filaments are the major structural component of the bacterial Z ring and are drivers of bacterial division. Crystal structures for FtsZ from some Gram-positive bacteria in the presence of GTP analogs suggest the possibility of a high-energy, “tense” conformation. It remains important t...

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Bibliographic Details
Main Authors: Kelsey M. McCoy, Keith J. Fritzsching, Ann E. McDermott
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:mBio
Subjects:
FtsZ
cytoskeleton
nuclear magnetic resonance
protein-protein interactions
structural biology
Online Access:https://journals.asm.org/doi/10.1128/mbio.02358-22

Internet

https://journals.asm.org/doi/10.1128/mbio.02358-22

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