Longitudinal Alzheimer’s Degeneration Reflects the Spatial Topography of Cholinergic Basal Forebrain Projections

Summary: The cholinergic neurons of the basal forebrain (BF) provide virtually all of the brain’s cortical and amygdalar cholinergic input. They are particularly vulnerable to neuropathology in early Alzheimer’s disease (AD) and may trigger the emergence of neuropathology in their cortico-amygdalar...

Full description

Bibliographic Details
Main Authors: Taylor W. Schmitz, Marieke Mur, Meghmik Aghourian, Marc-Andre Bedard, R. Nathan Spreng
Format: Article
Language:English
Published: Elsevier 2018-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718308969