Diagnostic Predictors of Immunotherapy Response in Head and Neck Squamous Cell Carcinoma

Diagnostic Predictors of Immunotherapy Response in Head and Neck Squamous Cell Carcinoma

Programmed cell death ligand-1 (PD-L1) binds PD-1 on CD<sup>8+</sup> lymphocytes, inhibiting their cytotoxic action. Its aberrant expression by head and neck squamous cell carcinoma (HNSCC) cells leads to immune escape. Pembrolizumab and nivolumab, two humanized monoclonal antibodies aga...

Full description

Bibliographic Details
Main Authors: Piero Giuseppe Meliante, Federica Zoccali, Marco de Vincentiis, Massimo Ralli, Carla Petrella, Marco Fiore, Antonio Minni, Christian Barbato
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Diagnostics
Subjects:
head and neck squamous cell carcinoma
immunotherapy
PD-1/PD-L1
immunotherapy molecular marker
immunotherapy resistance
pembrolizumab
Online Access:https://www.mdpi.com/2075-4418/13/5/862

Internet

https://www.mdpi.com/2075-4418/13/5/862

Similar Items