Effects of naringin and valproate interaction on liver steatosis and dyslipidaemia parameters in male C57BL6 mice

Effects of naringin and valproate interaction on liver steatosis and dyslipidaemia parameters in male C57BL6 mice

Valproate is a common antiepileptic drug whose adverse effects include liver steatosis and dyslipidaemia. The aim of our study was to see how natural flavonoid antioxidant naringin would interact with valproate and attenuate these adverse effects. For this reason we treated male C57BL6 mice with a c...

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Bibliographic Details
Main Authors: Jutrić David, Đikić Domagoj, Boroš Almoš, Odeh Dyna, Drozdek Sandra Domjanić, Gračan Romana, Dragičević Petar, Crnić Irena, Jurčević Irena Landeka
Format: Article
Language:English
Published: Sciendo 2022-04-01
Series:Arhiv za Higijenu Rada i Toksikologiju
Subjects:
acox1
cholesterol
dyslipidaemia
lipid regulating transcription factors
nrf2
oxidative stress
ppar-alpha
pgc-1 alpha
kolesterol
dislipidemija
ppar-alfa
pgc-1 alfa
oksidacijski stres
transkripcijski faktori za regulaciju lipida
Online Access:https://doi.org/10.2478/aiht-2022-73-3608

Internet

https://doi.org/10.2478/aiht-2022-73-3608

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