Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins

Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins

Abstract Intrinsically disordered proteins (IDPs) play crucial roles in cellular processes and hold promise as drug targets. However, the dynamic nature of IDPs remains poorly understood. Here, we construct a single-molecule electrical nanocircuit based on silicon nanowire field-effect transistors (...

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Bibliographic Details
Main Authors: Wenzhe Liu, Limin Chen, Dongbao Yin, Zhiheng Yang, Jianfei Feng, Qi Sun, Luhua Lai, Xuefeng Guo
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41018-x

Internet

https://doi.org/10.1038/s41467-023-41018-x

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