Visualizing single-molecule conformational transition and binding dynamics of intrinsically disordered proteins

Abstract Intrinsically disordered proteins (IDPs) play crucial roles in cellular processes and hold promise as drug targets. However, the dynamic nature of IDPs remains poorly understood. Here, we construct a single-molecule electrical nanocircuit based on silicon nanowire field-effect transistors (...

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Những tác giả chính: Wenzhe Liu, Limin Chen, Dongbao Yin, Zhiheng Yang, Jianfei Feng, Qi Sun, Luhua Lai, Xuefeng Guo
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Nature Portfolio 2023-08-01
Loạt:Nature Communications
Truy cập trực tuyến:https://doi.org/10.1038/s41467-023-41018-x