Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents

Assessment of the Biological Impact of SARS-CoV-2 Genetic Variation Using an Authentic Virus Neutralisation Assay with Convalescent Plasma, Vaccinee Sera, and Standard Reagents

In the summer of 2020, it became clear that the genetic composition of SARS-CoV-2 was changing rapidly. This was highlighted by the rapid emergence of the D614G mutation at that time. In the autumn of 2020, the project entitled “Agility” was initiated with funding from the Coalition for Epidemic Pre...

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Bibliographic Details
Main Authors: Naomi S. Coombes, Kevin R. Bewley, Yann Le Duff, Matthew Hurley, Lauren J. Smith, Thomas M. Weldon, Karen Osman, Steven Pullan, Neil Berry, Bassam Hallis, Sue Charlton, Yper Hall, Simon G. P. Funnell
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
SARS-CoV-2
SARS-CoV-2 variant
SARS-CoV-2 neutralisation assay
coronavirus
immune escape
Online Access:https://www.mdpi.com/1999-4915/15/3/633

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https://www.mdpi.com/1999-4915/15/3/633

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