Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes.

The endosomal pathway in neuronal dendrites is essential for membrane receptor trafficking and proper synaptic function and plasticity. However, the molecular mechanisms that organize specific endocytic trafficking routes are poorly understood. Here, we identify GRIP-associated protein-1 (GRASP-1) a...

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Bibliographic Details
Main Authors: Casper C Hoogenraad, Ioana Popa, Kensuke Futai, Emma Martinez-Sanchez, Phebe S Wulf, Thijs van Vlijmen, Bjorn R Dortland, Viola Oorschot, Roland Govers, Maria Monti, Albert J R Heck, Morgan Sheng, Judith Klumperman, Holger Rehmann, Dick Jaarsma, Lukas C Kapitein, Peter van der Sluijs
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2808209?pdf=render