The risk of type 2 oral polio vaccine use in post-cessation outbreak response

The risk of type 2 oral polio vaccine use in post-cessation outbreak response

Abstract Background Wild type 2 poliovirus was last observed in 1999. The Sabin-strain oral polio vaccine type 2 (OPV2) was critical to eradication, but it is known to revert to a neurovirulent phenotype, causing vaccine-associated paralytic poliomyelitis. OPV2 is also transmissible and can establis...

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Bibliographic Details
Main Authors: Kevin A. McCarthy, Guillaume Chabot-Couture, Michael Famulare, Hil M. Lyons, Laina D. Mercer
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Medicine
Subjects:
Poliovirus
Eradication
Oral polio vaccine
Cessation
Vaccine-derived poliovirus
Online Access:http://link.springer.com/article/10.1186/s12916-017-0937-y

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http://link.springer.com/article/10.1186/s12916-017-0937-y

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