Early removal of the infrapatellar fat pad/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs

Early removal of the infrapatellar fat pad/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs

Abstract Background The infrapatellar fat pad (IFP) is the largest adipose deposit in the knee; however, its contributions to the homeostasis of this organ remain undefined. To determine the influence of the IFP and its associated synovium (IFP/synovium complex or IFP/SC) on joint health, this study...

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Bibliographic Details
Main Authors: Maryam F. Afzali, Lauren B. Radakovich, Madeline M. Sykes, Margaret A. Campbell, Kayley M. Patton, Joseph L. Sanford, Nicole Vigon, Ryan Ek, Gerardo E. Narez, Angela J. Marolf, Katie J. Sikes, Tammy L. Haut Donahue, Kelly S. Santangelo
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Arthritis Research & Therapy
Subjects:
Osteoarthritis
Infrapatellar fat pad/synovium complex
Gait
Inflammation
Biomechanics
Trace elements
Online Access:https://doi.org/10.1186/s13075-022-02971-y

Internet

https://doi.org/10.1186/s13075-022-02971-y

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