The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons

The Prenylflavonoid ENDF1 Overrules Central Nervous System Growth Inhibitors and Facilitates Regeneration of DRG Neurons

Restoration of neuronal connectivity after lesion of the central nervous system, such as spinal cord injury, is one of the biggest challenges in modern medicine. In particular, the accumulation of axon growth inhibitory factors at the site of injury constitutes a major obstacle to structural and thu...

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Bibliographic Details
Main Authors: Lara Bieler, Michael Vogl, Michael Kirchinger, Corinna Urmann, Herbert Riepl, Christine Bandtlow, Lars Klimaschewski, Ludwig Aigner, Sebastien Couillard-Despres
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
flavonoids
dorsal root ganglions
DRG neurons
axonal outgrowth
semaphorin
ephrin
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00332/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2019.00332/full

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