Synthesis, structural examination, molecular interaction analysis, invitro and insilico anticancer activity investigation of a new curcumin derivative: 1- (4 – chlorobenzoyl) - 3, 5 - bis ((E) - 4 - methoxybenzylidene) piperidin - 4 – one

Synthesis, structural examination, molecular interaction analysis, invitro and insilico anticancer activity investigation of a new curcumin derivative: 1- (4 – chlorobenzoyl) - 3, 5 - bis ((E) - 4 - methoxybenzylidene) piperidin - 4 – one

The title material, C28H24ClNO4, was synthesized using the Claisen-Schmidt condensation reaction and Schotten-Baumann reaction methods and crystallized. Geometrical parameters were determined for the grown crystal using the Single Crystal X-Ray Diffraction (SCXRD) technique. The title compound has b...

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Bibliographic Details
Main Authors: A. Anish Fathima, Varuna Kumaravel, D. Reuben Jonathan, Senthil Kumar Sadasivam, R. Yuvashri, G. Usha
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Chemical Physics Impact
Subjects:
Curcumin derivative
SCXRD
NMR
FTIR
Anticancer activity
In-silico investigation
Online Access:http://www.sciencedirect.com/science/article/pii/S2667022424001038

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http://www.sciencedirect.com/science/article/pii/S2667022424001038

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