Benchmarking MicrobIEM – a user-friendly tool for decontamination of microbiome sequencing data

Benchmarking MicrobIEM – a user-friendly tool for decontamination of microbiome sequencing data

Abstract Background Microbiome analysis is becoming a standard component in many scientific studies, but also requires extensive quality control of the 16S rRNA gene sequencing data prior to analysis. In particular, when investigating low-biomass microbial environments such as human skin, contaminan...

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Bibliographic Details
Main Authors: Claudia Hülpüsch, Luise Rauer, Thomas Nussbaumer, Vera Schwierzeck, Madhumita Bhattacharyya, Veronika Erhart, Claudia Traidl-Hoffmann, Matthias Reiger, Avidan U. Neumann
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Biology
Subjects:
Low-biomass microbiome
16S rRNA gene sequencing
Bioinformatic decontamination
Negative control
Youden’s index
Decontam
Online Access:https://doi.org/10.1186/s12915-023-01737-5

Internet

https://doi.org/10.1186/s12915-023-01737-5

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