In silico molecular docking and dynamic simulation of anti-cholinesterase compounds from the extract of Catunaregam spinosa for possible treatment of Alzheimer's disease

In silico molecular docking and dynamic simulation of anti-cholinesterase compounds from the extract of Catunaregam spinosa for possible treatment of Alzheimer's disease

Alzheimer's disease (AD), is characterized by a progressive loss of cognitive abilities as well as behavioral symptoms including disorientation, trouble solving problems, personality and mood changes. Acetylcholinesterase (AChE) is a promising target for symptomatic improvement in AD due to its...

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Bibliographic Details
Main Authors: Sathish Thandivel, Poovarasan Rajan, Tamizharasan Gunasekar, Abisek Arjunan, Sulekha Khute, Srinivasa Rao Kareti, Subash Paranthaman
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Alzheimer's disease
In silico
Catunaregam spinosa
ADMET
Acetylcholinesterase
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024039112

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http://www.sciencedirect.com/science/article/pii/S2405844024039112

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