Cholesterol in Class C GPCRs: Role, Relevance, and Localization

G-protein coupled receptors (GPCRs), one of the largest superfamilies of cell-surface receptors, are heptahelical integral membrane proteins that play critical roles in virtually every organ system. G-protein-coupled receptors operate in membranes rich in cholesterol, with an imbalance in cholestero...

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Bibliographic Details
Main Authors: Ugochi H. Isu, Shadi A Badiee, Ehsaneh Khodadadi, Mahmoud Moradi
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/3/301