Cholesterol in Class C GPCRs: Role, Relevance, and Localization
G-protein coupled receptors (GPCRs), one of the largest superfamilies of cell-surface receptors, are heptahelical integral membrane proteins that play critical roles in virtually every organ system. G-protein-coupled receptors operate in membranes rich in cholesterol, with an imbalance in cholestero...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
|
Series: | Membranes |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0375/13/3/301 |