TXNIP regulates peripheral glucose metabolism in humans.

TXNIP regulates peripheral glucose metabolism in humans.

<h4>Background</h4>Type 2 diabetes mellitus (T2DM) is characterized by defects in insulin secretion and action. Impaired glucose uptake in skeletal muscle is believed to be one of the earliest features in the natural history of T2DM, although underlying mechanisms remain obscure.<h4&g...

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Main Authors: Hemang Parikh, Emma Carlsson, William A Chutkow, Lovisa E Johansson, Heidi Storgaard, Pernille Poulsen, Richa Saxena, Christine Ladd, P Christian Schulze, Michael J Mazzini, Christine Bjørn Jensen, Anna Krook, Marie Björnholm, Hans Tornqvist, Juleen R Zierath, Martin Ridderstråle, David Altshuler, Richard T Lee, Allan Vaag, Leif C Groop, Vamsi K Mootha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS Medicine
Online Access:https://doi.org/10.1371/journal.pmed.0040158

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https://doi.org/10.1371/journal.pmed.0040158

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