Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model.

Spatio-Temporal Patterns of Demyelination and Remyelination in the Cuprizone Mouse Model.

Cuprizone administration in mice provides a reproducible model of demyelination and spontaneous remyelination, and has been useful in understanding important aspects of human disease, including multiple sclerosis. In this study, we apply high spatial resolution quantitative MRI techniques to establi...

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Bibliographic Details
Main Authors: Ian Tagge, Audrey O'Connor, Priya Chaudhary, Jim Pollaro, Yosef Berlow, Megan Chalupsky, Dennis Bourdette, Randy Woltjer, Mac Johnson, William Rooney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4824475?pdf=render

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http://europepmc.org/articles/PMC4824475?pdf=render

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