Inflammasome Activation Contributes to Interleukin-23 Production in Response to <named-content content-type="genus-species">Clostridium difficile</named-content>
ABSTRACT Clostridium difficile is the most common hospital-acquired pathogen, causing antibiotic-associated diarrhea in over 250,000 patients annually in the United States. Disease is primarily mediated by toxins A and B, which induce potent proinflammatory signaling in host cells and can activate...
Hauptverfasser: | Carrie A. Cowardin, Sarah A. Kuehne, Erica L. Buonomo, Chelsea S. Marie, Nigel P. Minton, William A. Petri |
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Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
American Society for Microbiology
2015-02-01
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Schriftenreihe: | mBio |
Online Zugang: | https://journals.asm.org/doi/10.1128/mBio.02386-14 |
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