Inflammasome Activation Contributes to Interleukin-23 Production in Response to <named-content content-type="genus-species">Clostridium difficile</named-content>
ABSTRACT Clostridium difficile is the most common hospital-acquired pathogen, causing antibiotic-associated diarrhea in over 250,000 patients annually in the United States. Disease is primarily mediated by toxins A and B, which induce potent proinflammatory signaling in host cells and can activate...
Main Authors: | Carrie A. Cowardin, Sarah A. Kuehne, Erica L. Buonomo, Chelsea S. Marie, Nigel P. Minton, William A. Petri |
---|---|
Format: | Article |
Language: | English |
Published: |
American Society for Microbiology
2015-02-01
|
Series: | mBio |
Online Access: | https://journals.asm.org/doi/10.1128/mBio.02386-14 |
Similar Items
-
Bone Marrow Dendritic Cells from Mice with an Altered Microbiota Provide Interleukin 17A-Dependent Protection against <named-content content-type="genus-species">Entamoeba histolytica</named-content> Colitis
by: Stacey L. Burgess, et al.
Published: (2014-12-01) -
Dipicolinic Acid Release by Germinating <named-content content-type="genus-species">Clostridium difficile</named-content> Spores Occurs through a Mechanosensing Mechanism
by: Michael B. Francis, et al.
Published: (2016-12-01) -
Active and Secretory IgA-Coated Bacterial Fractions Elucidate Dysbiosis in <named-content content-type="genus-species">Clostridium difficile</named-content> Infection
by: Mária Džunková, et al.
Published: (2016-06-01) -
Minimalistic Cellulosome of the Butanologenic Bacterium <named-content content-type="genus-species">Clostridium saccharoperbutylacetonicum</named-content>
by: Bosmat Levi Hevroni, et al.
Published: (2020-04-01) -
Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from <named-content content-type="genus-species">Clostridium difficile</named-content> Ribotype 027
by: Zeyu Peng, et al.
Published: (2019-10-01)