Maresin 1 Mitigates Sepsis-Associated Acute Kidney Injury in Mice via Inhibition of the NF-κB/STAT3/MAPK Pathways

Maresin 1 Mitigates Sepsis-Associated Acute Kidney Injury in Mice via Inhibition of the NF-κB/STAT3/MAPK Pathways

Acute kidney injury (AKI) is one of the most common and serious complications of sepsis in which the inflammatory cascade plays a crucial role. There is now increasing evidence that lipid mediators derived from the omega-3 fatty acid docosahexaenoic acid (DHA) have potent anti-inflammatory effects t...

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Bibliographic Details
Main Authors: ShuJun Sun, JiaMei Wang, JingXu Wang, FuQuan Wang, ShangLong Yao, HaiFa Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Pharmacology
Subjects:
Maresin 1
Sepsis
acute kidney injury
inflammatory
cecal ligation and puncture
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01323/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01323/full

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