Seropositivity-Dependent Association between LINE-1 Methylation and Response to Methotrexate Therapy in Early Rheumatoid Arthritis Patients
Background: Methotrexate (MTX) is considered the first choice among disease-modifying anti-rheumatic drugs (DMARDs) for rheumatoid arthritis (RA) treatment. However, response to it varies as approximately 40% of the patients do not respond and would lose the most effective period of treatment time....
Main Authors: | Amin Ravaei, Lia Pulsatelli, Elisa Assirelli, Riccardo Meliconi, Jacopo Ciaffi, Elisa Gremese, Barbara Tolusso, Carlo Salvarani, Marcello Govoni, Michele Rubini |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/13/11/2012 |
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