Label-free Analysis of CD8+ T Cell Subset Proteomes Supports a Progressive Differentiation Model of Human-Virus-Specific T Cells

Label-free Analysis of CD8+ T Cell Subset Proteomes Supports a Progressive Differentiation Model of Human-Virus-Specific T Cells

Summary: Pathogens trigger T cells to express distinct sets of effector proteins. To better understand the molecular mechanisms that drive functional specification, we used high-resolution mass spectrometry and label-free protein quantification to measure proteomic differences between the seven larg...

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Bibliographic Details
Main Authors: Michiel C. van Aalderen, Maartje van den Biggelaar, Ester B.M. Remmerswaal, Floris P.J. van Alphen, Alexander B. Meijer, Ineke J.M. ten Berge, René A.W. van Lier
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717304898

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http://www.sciencedirect.com/science/article/pii/S2211124717304898

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