Novel Pyrimidine Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Molecular Modeling Studies

Novel Pyrimidine Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Molecular Modeling Studies

The heterocyclic ring system of pyrido [2,3-<i>d</i>]pyrimidines is a privileged scaffold in medicinal chemistry, possessing several biological activities. The synthesis of the pyrimidine derivatives was performed via the condensation of a suitable <i>α,β</i>-unsaturated keto...

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Bibliographic Details
Main Authors: Malama Myriagkou, Evangelia Papakonstantinou, Georgia-Eirini Deligiannidou, Alexandros Patsilinakos, Christos Kontogiorgis, Eleni Pontiki
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Molecules
Subjects:
antioxidant
anti-inflammatory
cytotoxicity
HaCaT
pyrimidine derivatives
LOX inhibition
Online Access:https://www.mdpi.com/1420-3049/28/9/3913

Internet

https://www.mdpi.com/1420-3049/28/9/3913

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