Studying the Mechanobiology of Aortic Endothelial Cells Under Cyclic Stretch Using a Modular 3D Printed System

Studying the Mechanobiology of Aortic Endothelial Cells Under Cyclic Stretch Using a Modular 3D Printed System

Here, we describe a motorized cam-driven system for the cyclic stretch of aortic endothelial cells. Our modular design allows for generating customized spatiotemporal stretch profiles by varying the profile and size of 3D printed cam and follower elements. The system is controllable, compact, inexpe...

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Bibliographic Details
Main Authors: Sergio Aguilera Suarez, Nadia Chandra Sekar, Ngan Nguyen, Austin Lai, Peter Thurgood, Ying Zhou, Scott Needham, Elena Pirogova, Khashayar Khoshmanesh, Sara Baratchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
mechanobiology
endothelial
cyclic stretch
3D printing
mechanotransduction
biomechanics
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.791116/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2021.791116/full

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