Early Changes in Exo- and Endocytosis in the EAE Mouse Model of Multiple Sclerosis Correlate with Decreased Synaptic Ribbon Size and Reduced Ribbon-Associated Vesicle Pools in Rod Photoreceptor Synapses

Early Changes in Exo- and Endocytosis in the EAE Mouse Model of Multiple Sclerosis Correlate with Decreased Synaptic Ribbon Size and Reduced Ribbon-Associated Vesicle Pools in Rod Photoreceptor Synapses

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system that finally leads to demyelination. Demyelinating optic neuritis is a frequent symptom in MS. Recent studies also revealed synapse dysfunctions in MS patients and MS mouse models. We previously reported alterations of...

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Bibliographic Details
Main Authors: Ajay Kesharwani, Karin Schwarz, Ekta Dembla, Mayur Dembla, Frank Schmitz
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
optic neuritis
EAE mouse model
rod photoreceptor
ribbon synapses
synaptic ribbon
Online Access:https://www.mdpi.com/1422-0067/22/19/10789

Internet

https://www.mdpi.com/1422-0067/22/19/10789

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